Reviewed by Jesse Koskey, MD. Dr. Koskey has no financial relationships with companies related to this material.
REVIEW OF: Clark KD et al, JAMA Netw Open 2025;8(9):e2527780
STUDY TYPE: Retrospective cohort
More patients with gender dysphoria (GD) are seeking legal and medical transition. The idea that they may later regret transitioning has led to both clinical and political debate. Clark and colleagues’ Swedish registry study examined the stability of legal gender transitions.
In Sweden, adults seeking a legal gender change must be at least 18, undergo psychiatric evaluation, receive a diagnosis of GD, and be prescribed gender-affirming treatment. Nonbinary legal genders aren’t permitted. Researchers followed 7,293 people newly diagnosed with GD from 2013 to 2023, tracking who changed their legal gender and who later changed it back.
About one-third of the cohort (2,467 individuals) obtained a legal gender change. Over 10 years, the probability of doing so reached about 58%, with most changes occurring 2–3 years after diagnosis—likely reflecting long evaluation and administrative delays. Rates were similar regardless of sex assigned at birth.
Reversals were rare. Only 21 people changed their legal gender back, or 0.9% of those who transitioned. The 10-year probability of keeping a new legal gender was nearly 98%. Those who reversed didn’t differ meaningfully in age, background, or timing, and no clear high-risk subgroup emerged.
CARLAT TAKE
It’s clear that for adult patients who met criteria for legal transition in Sweden, legal gender changes were highly stable.
Please see our Terms and Conditions, Privacy Policy, Subscription Agreement, Use of Cookies, and Hardware/Software Requirements to view our website.
© 2026 Carlat Publishing, LLC and Affiliates, All Rights Reserved.