A decades-old vascular drug unexpectedly lifts mood—offering a fresh angle on treatment-resistant depression.

Long-acting injectables extend stability in bipolar disorder, delaying relapse more effectively than oral antipsychotics

Do SSRIs unmask bipolar disorder in youth? A new Swedish cohort study addresses whether SSRIs trigger mania in children and adolescents with unipolar depression. Learn which risk factors warrant closer monitoring.

Many patients with schizophrenia or recurrent psychotic disorders want to reduce or stop their antipsychotic drugs to minimize adverse effects like sedation, weight gain, and emotional blunting, all of which can impair social functioning.

Injectable naltrexone can be an effective treatment for opioid use disorder, but it requires complete abstinence before initiation—a process that can take more than a week and cause significant discomfort. Here, researchers evaluate a new protocol designed to accelerate this induction period and improve patient access.