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Home » pharmacology

Articles Tagged with ''pharmacology''

Gabapentin Enacarbil XR Efficacy Less Than Expected for AUD

August 1, 2019
Thomas Jordan, MD
From The Carlat Addiction Treatment Report
Issue Links: Learning Objectives | Editorial Information
Thomas Jordan, MD Dr. Jordan has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
This 2019 randomized, double-blind, placebo- controlled trial study casts doubt on using gabapentin enacarbil extended-release (GE-XR) (Horizant), an extended-release version of gabapentin, for treatment in patients with alcohol use disorder
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Can Buprenorphine Improve PTSD Symptoms?

August 1, 2019
Thomas Jordan, MD
From The Carlat Addiction Treatment Report
Issue Links: Learning Objectives | Editorial Information
Thomas Jordan, MD Dr. Jordan has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
This 2019 retrospective study examines the potential benefits of using buprenorphine/naloxone to treat co-occurring PTSD and opioid use disorder.
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Esketamine Gets FDA Approval

July 3, 2019
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Michael Posternak, MD. Psychiatrist in private practice, Boston, MA. Dr. Posternak has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
On March 5, 2019, the FDA approved esketamine (Spravato) nasal spray as add-on therapy to traditional antidepressant medications for treatment-resistant depression (TRD). In this article, I will describe the events that led to esketamine’s development, review the data submitted to the FDA, and discuss what the future might hold for esketamine.
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Risk Evaluation and Mitigation Strategy (REMS) Programs

July 3, 2019
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Certain psychiatric treatments require both the healthcare provider and patient to enroll in a Risk Evaluation and Mitigation Strategy (REMS) program before they are administered. Here are links to enroll.
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Medication Side Effects: Nausea, Sweating, and Dry Mouth

July 3, 2019
Rajnish Mago, MD
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Rajnish Mago, MDRajnish Mago, MD
Editor-in-Chief of Simple and Practical Mental Health and author of Side Effects of Psychiatric Medications: Prevention, Assessment, and Management Dr. Mago has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Does ginger ale treat nausea? Not really, but Dr. Mago has some better ideas, and this interview is packed with new and practical ways to manage common side effects of psychiatric medications.
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A New Dopamine and Norepinephrine Reuptake Inhibitor for Excessive Sleepiness

July 3, 2019
Talia Puzantian, Chris Aiken, MD, and Chris Aiken
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Talia Puzantian, PharmD, BCPP Chris Aiken, MD. Drs. Puzantian and Aiken have disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Solriamfetol (Sunosi) was just approved for excessive daytime sleepiness in narcolepsy and sleep apnea, but it may have important psychiatric effects as well.
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Brexanolone (Zulresso) for Postpartum Depression

July 3, 2019
Talia Puzantian, Chris Aiken, MD, and Chris Aiken
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Talia Puzantian, PharmD, BCPP Chris Aiken, MD Drs. Puzantian and Aiken have disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Every week of depression takes a toll on infant development, so this rapid-acting treatment fills a unique need. Here we review the clinical data and the pragmatics of getting patients connected with the therapy.
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RESEARCH UPDATE

A New Proposal for SSRI Withdrawal

July 3, 2019
Greg Sazima, MD and Chris Aiken, MD
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue

Drs. Sazima and Aiken have disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity.

The way we taper serotonergic antidepressants may need to be rethought, and this study suggests a new method.
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SSRI withdrawal symptoms

July 3, 2019
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Use this PDF tool to check if the patient is having any SSRI withdrawal symptoms at baseline.
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Mood Stabilizers and Stroke Risk in Bipolar Disorder

July 3, 2019
Thomas Jordan, MD.
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Thomas Jordan, MD. Dr. Jordan has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity
Why does stroke matter in bipolar disorder? Because it’s the leading cause of death for these patients. Some mood stabilizers raise the stroke risk, while others do not.
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