St. John’s wort bridges complementary and conventional approaches.

Sarcosine is an amino acid that enhances NMDA receptor function, a glutamatergic mechanism with relevance to schizophrenia and depression.

Saffron is probably the oldest antidepressant in continuous use, originating in the Persian Empire as a cure for melancholy, circa 600 BC. 

SAMe is a small molecule with a long name.

Rhodiola rosea has a long history of use but a short list of clinical trials.

Red wine is rich in resveratrol, from the skin of grapes.

The racetams are a family of synthetic compounds, including piracetam, aniracetam, and pramiracetam. 

Promising but unproven supplements.

Probiotics have become one of the most talked-about complementary approaches in psychiatry, thanks to a growing understanding of the gut-brain axis. 

Phosphatidylserine (PS) is a fat molecule (phospholipid) that is packed into the inner walls of neuronal membranes, where it helps maintain membrane integrity, myelin structure, and synaptic function.