Begin preparation at least six months before conception to ensure stability, switch to safer medications, and manage psychosocial stressors.

A treament overview of Methylphenidate and Amphetamine medicatoins for ADHD.

Drug-drug interactions are critical to monitor in older adults due to the high prevalence of polypharmacy in this population. 

If a patient is tapering off SSRIs completely — rather than switching to another antidepressant — a hyperbolic taper minimizes the risk of withdrawal.

There are many effective medications for panic disorder, including tricyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and monoamine oxidase inhibitors (MAOIs). 

It's frustrating for both patients and doctors when depression treatments fall short, and unfortunately, this is a common problem. 

When Dr. Chris Aiken opened a psychotherapy practice in Western North Carolina, treatment-resistant depression wasn’t a specialty he planned for — it was what walked through the door. Most patients arrived having already failed one or more SSRIs prescribed in primary care. The standard next steps — raising the dose, switching classes, adding bupropion, buspirone, or a stimulant — often weren’t enough.

In August 2024, the American Journal of Psychiatry published a landmark update on PTSD by Arieh Shalev, MD, and colleagues at NYU — a comprehensive look at the diagnosis, neuroscience, and treatment of one of psychiatry’s most complex conditions. Dr. Chris Aiken, Editor-in-Chief of The Carlat Psychiatry Report, and his co-host Kellie Newsome, PMHNP took a deep dive into that article in this five-part podcast series.

Our most-listened-to podcast series is now available in full — all ten episodes, free to stream. Dr. Chris Aiken, Editor-in-Chief of The Carlat Psychiatry Report, and Kellie Newsome, PMHNP distill ten essential principles every prescriber should know about psychopharmacology: the rules that keep patients safe, the pitfalls that catch clinicians off guard, and the evidence that should guide your prescribing every day.

One of our most popular 2025 podcast series is now available in full. Dr. Chris Aiken, Editor-in-Chief of The Carlat Psychiatry Report, and Kellie Newsome, PMHNP share expert tips on drug titration — including psych meds that are better tolerated when started faster, and one that must be launched at a high dose and then tapered down to a low maintenance dose. (Spoiler: it’s not buprenorphine.)