Low doses of aripiprazole, brexpiprazole, or cariprazine offer modest but meaningful gains for TRD.

Zuranolone shows modest short-term benefit in major depression, but results fall short of meaningful clinical impact

Postpartum depression (PPD) affects 12% of mothers and takes a toll on infant and family health. 

Alcohol use disorder (AUD) is notoriously difficult to treat, with pharmacological options often underutilized or only modestly effective. But what if a medication already used for diabetes and obesity could help?