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Home » Topics » Addiction Treatment

Addiction Treatment
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Research Update

Cannabis Use Frequency and Cannabis Use Disorder

June 20, 2025
Aniruddha Deka, MD
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Aniruddha Deka, MD. Dr. Deka has no financial relationships with companies related to this material.

Prevalence and frequency of cannabis use have increased as restrictions have been eased across the country. Here, researchers asked the question: Does frequency of cannabis use affect the likelihood of developing cannabis use disorder? The answer may surprise you.


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Research Update

A Rapid Initiation Protocol for Long-Acting Injectable Naltrexone for Opioid Use Disorder

April 1, 2025
Noah Capurso, MD, MHS
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Noah Capurso, MD, MHS. Dr. Capurso has no financial relationships with companies related to this material. 

Injectable naltrexone can be an effective treatment for opioid use disorder, but it requires complete abstinence before initiation—a process that can take more than a week and cause significant discomfort. Here, researchers evaluate a new protocol designed to accelerate this induction period and improve patient access.


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Learning Objectives, Medical Issues in Addiction, CATR, April/May/June 2025

April 1, 2025
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

After reading these articles, you should be able to…


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CATR_QA2_Joseph D'Orazio_headshot_sm.png
Expert Q&A

Xylazine and Peripheral Wounds

April 1, 2025
Joseph D’Orazio, MD
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Joseph D’Orazio, MD, Associate Professor of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ. Dr. D’Orazio has no financial relationships with companies related to this material.

Xylazine is a non-opioid sedative commonly added surreptitiously to illicit opioids. One particularly challenging adverse effect of xylazine exposure is the development of peripheral wounds, some of which can be severe, necessitating surgical intervention and even amputation. In this interview, Dr. D’Orazio teaches us how these wounds might be caused, how to discuss them with your patients, and the best treatment approach.


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Expert Q&A

Substance Use and Dental Health: What Clinicians Need to Know

April 1, 2025
Aviv Ouanounou, DDS, MSc
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Aviv Ouanounou, DDS, MSc, Associate Professor, University of Toronto, Toronto, Canada. 

Dr. Ouanounou has no financial relationships with companies related to this material. 

Substance use is associated with many dental problems, some of which can even be life threatening. Here, Dr. Ouanounou discusses which specific dental issues addiction treatment providers need to be on the lookout for. He covers the basics of dental examination and teaches us when referral to specialty care is warranted.


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Clinical Update

Understanding Viral Hepatitis in the Context of Addiction Psychiatry

April 1, 2025
From The Carlat Addiction Treatment Report
Issue Links: Editorial Information | PDF of Issue

Danielle Herman. Case Western Reserve University School of Medicine, Cleveland, OH.

Raquel Rozner, MD. Gastroenterology Associates, PC, Stratford, CT; Bridgeport Hospital/Yale New Haven Health, Bridgeport, CT.

Akhil Anand, MD. Department of Psychiatry and Psychology, Cleveland Clinic; Department of Psychiatry, University Hospitals Medical Center, Cleveland, OH.

Ms. Herman, Dr. Rozner, and Dr. Anand have no financial relationships with companies related to this material. 

Hepatitis B and C are highly prevalent in people who use drugs and can result in significant morbidity and mortality due to progressive liver disease. In this article, we cover all the basics, including screening, symptoms, and relevant laboratory testing. We give tips to provide your patients on hepatitis prevention and when to refer them to specialists for treatment. 


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Clinical Guidance

How to Manage and Taper Buprenorphine

January 1, 2025
Noah Capurso, MD, MHS, Talia Puzantian, PharmD, BCPP, and Daniel Carlat, MD

Dr. Capurso, Dr. Puzantian, and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

After you have initiated buprenorphine, see patients weekly at first to make sure the dose is right.




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Clinical Guidance

How to Discuss and Initiate Extended-Release Naltrexone (Vivitrol)

January 1, 2025
Noah Capurso, MD, MHS, Talia Puzantian, PharmD, BCPP, and Daniel Carlat, MD

Dr. Capurso, Dr. Puzantian, and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Extended-release naltrexone injection (XR-NTX) is an effective medication for some patients with opioid use disorder (OUD).




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Clinical Guidance

How to Discuss and Initiate Buprenorphine

January 1, 2025
Noah Capurso, MD, MHS, Talia Puzantian, PharmD, BCPP, and Daniel Carlat, MD

Dr. Capurso, Dr. Puzantian, and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Induction refers to the process of starting a patient on buprenorphine (with or without naloxone; the combination product is most often preferred).




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Clinical Guidance

How to Choose the Right Medications for Opioid Use Disorder

January 1, 2025
Noah Capurso, MD, MHS, Talia Puzantian, PharmD, BCPP, and Daniel Carlat, MD

Dr. Capurso, Dr. Puzantian, and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

The purpose of this fact sheet is not to provide details on pharmacology or the use of these medications, but rather to help you decide which might be best for a given patient.




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