Tobacco smoking and major depression are highly comorbid, and depressed patients usually have a tougher time quitting than their non-depressed counterparts. In this research study, investigators compared the efficacy of anti-smoking medications in those with depression. The results may surprise you.

Contingency management (CM) is a clinical approach that leverages principles of operant conditioning to treat stimulant use disorder. In this interview, Dr. DePhilippis explains how CM incentivizes recovery behaviors like abstinence with immediate rewards, making it an effective treatment tool. Learn how this evidence-based strategy works, why it’s considered the gold standard for treating stimulant use disorder, and the challenges of implementing CM in real-world settings.

The interview with Dr. Hurley provides crucial insights into the world of psychostimulants, their misuse, and the emerging Fourth Wave of the Overdose Epidemic. Dr. Hurley discusses everything from the differences between stimulants like methamphetamine and cocaine to the importance of harm reduction strategies and evidence-based treatments for stimulant use disorder.

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It was once thought that moderate alcohol intake was protective against cardiovascular disease. However, new research has revealed flaws in the methodology of these old studies and instead finds that even in moderation, alcohol does not have health benefits and can increase mortality at lower doses than once thought, particularly for women.

Everyone knows that it is dangerous to drive while under the influence of alcohol—but what about cannabis? This study adds to a growing body of evidence that cannabis can be hazardous to safety on the road, a particularly important message to get out to patients as legalization becomes increasingly common.

Buprenorphine and methadone are both first-line treatments for opioid use disorder during pregnancy. Though this recommendation has been long-standing, it is based on a rather small study that is nearly 15 years old. In the current study, researchers revisit the question of how best to treat opioid use disorder during pregnancy with a large observational cohort study.