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Research Update

Why Should We Care About Hyperprolactinemia With Antipsychotic Use?

April 1, 2023

Lara Tang, MD. Dr. Tang has no financial relationships with companies related to this material.

Highly prolactin-elevating antipsychotics, like haloperidol, risperidone, and paliperidone, are associated with an elevated risk of breast cancer, particularly among young women.

CLINICAL UPDATE

Psychiatric Medication–Induced Hyperprolactinemia

July 1, 2022

Niki Karavitaki, MD. Senior Clinical Lecturer, Institute of Metabolism and Systems Research, University of Birmingham. Honorary Consultant Endocrinologist, Queen Elizabeth Hospital. Birmingham, UK.

Athanasios Fountas, MD. Clinical Research Fellow, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham. Birmingham, UK.

Dr. Karavitaki has disclosed that she has given webinars for Pfizer on the topic of acromegaly in February 2021 and January 2022. Dr. Hendrick has reviewed the content of this interview and determined that there is no commercial bias as a result of these financial relationships. Dr. Fountas has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Medication–induced hyperprolactinemia is more common than you might think and it can produce detrimental long-term health sequelae. Two endocrinologists -- Drs Fountas and Karavitakis – review the work-up and management of this common side effect.

Vitamin B6 Lowers Prolactin on Antipsychotics

March 4, 2022

Brian Miller, MD, PhD, MPH.

Brian Miller, MD, PhD, MPH. Dr. Miller has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Higher antipsychotic doses are more likely to elevate prolactin. Enter: Vitamin B6.

Sex-Based Treatment of Schizophrenia

July 14, 2021

Jayashri Kulkarni, MBBS, PhD, FAHMS

Jayashri Kulkarni, MBBS, PhD, FAHMS

Professor of Psychiatry, Monash University.Director, Monash Alfred Psychiatry Research Center, Melbourne, Australia.

Dr. Kulkarni has disclosed no relevant financial or other interest in any commercial companies pertaining to this educational activity.

We can use our knowledge of gender differences in schizophrenia, argues Dr. Kulkarni, to inform and broaden our interventions for female patients.

Hyperprolactinemia: Effective Treatment With Aripiprazole

May 21, 2021

Christina Guest, MD

Christina Guest, MD Dr. Guest has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Many antipsychotic medications produce hyperprolactinemia, leading to breast enlargement in men and missed menstrual cycles in women. A clever intervention reduces patients' prolactin levels.