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A Narcolepsy Primer, With a Focus on Xyrem

Narcolepsy affects about 1 out of 2000 people, for a prevalence rate of 0.05%. This puts it officially in the category of rare diseases. So why are we asking you to read about such a rare disorder? Partly because there’s a lot of comorbidity between narcolepsy and most psychiatric disorders. And partly because Jazz Pharmaceuticals is placing lots of ads in psychiatric journals urging us to diagnose more narcolepsy so that we’ll use their new drug Xyrem. Read More

What basic questions should we be asking our patients who complain of sleep problems? We talk to Robert S. Rosenberg, DO, FCCP, to get his insight on sleep disorders, sleep apnea, restless leg syndrome, sleep studies, and benzodiazepines. Read More

Should We Add Stimulants to SSRIs to Treat Geriatric Depression?

Geriatric depression often presents with apathy, low energy and motivation, and cognitive decline, so theoretically stimulants are a natural choice. Past studies of combining stimulants with antidepressants have been mainly small open trials, with mostly positive results. But we haven’t seen the kind of rigorous double-blind methodology we’d like. A new study fills that gap. Read More

Rexulti for Schizophrenia and MDD: Is It Abilify, Round 2?

On July 10, the U.S. Food and Drug Administration (FDA) approved Otsuka and Lundbeck’s Rexulti (brexpiprazole) for schizophrenia and as an add-on to antidepressants for adults with depression. As the name suggests, it’s chemically and structurally related to aripiprazole (Abilify). Read More

Medication Fact Book for Psychiatric Practice, Sixth Edition (2022)
Guidance, clinical pearls, and bottom-line assessments covering the medications you use in your...
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General Psychiatry
Using SAMe In Clinical Practice with Garrett Rossi, MD
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General Psychiatry
Elvis, Adderall, and a Broken Heart - Part 1
A new medical investigation changes our understanding of Elvis Presley’s untimely death and offer some pearls for modern psychiatric practice.
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