A Closer Look at Alpha-2 Agonists for ADHD
The Carlat Psychiatry Report, Volume 19, Number 3, March 2021
C. Jason Mallo, DO.
Attending Psychiatrist, Maine Medical Center, Portland, Maine.
Dr. Mallo has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Now that guanfacine ER (Intuniv) and clonidine ER (Kapvay) have gone generic, we review the 40-years of research that earned them FDA approval in ADHD. Along the way we’ll consider their off-label use in anxiety, addiction, insomnia, and self-harm. Plus: When to use the ER, the instant release, or the oft-forgotten transdermal patch.