Clear, engaging, and practical updates on clinical psychiatry.

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Pharmacogenetics: Not Quite Ready for Prime Time?

June 7, 2021 | Podcasts

Clinicians are inundated with ads for genetic testing, but is genetic testing currently helpful for informing clinical care? The latest issue of The Carlat Child Psychiatry Report includes an interview with Dr. Aaron Besterman, who’s an adult and child & adolescent...


Bipolar, Barbiturates, and Punk Rock

May 31, 2021 | Podcasts

Brian Wilson, Lou Reed, and Ian Curtis all created new music genres, and each of them is reputed to have had bipolar disorder. We look at the evidence behind that, and learn a few things about psychiatry and creativity along...


How COVID Affects the Brain

May 24, 2021 | Podcasts

The psychiatric syndromes caused by COVID infection may look like commonplace DSM-5 disorders, but the cause and treatment may be different. Reference: Boldrini M, Canoll PD, Klein RS. How COVID-19 Affects the Brain. JAMA Psychiatry. 2021 Mar 26. Published On: 5/24/2021...


13 Ways to Use Topiramate

May 17, 2021 | Podcasts

We ask the big questions: Is topiramate a drug or a sugar? Do you need to use the FDA-approved combo pill for weight loss? And which of its 13 off-label psychiatric uses are ready for clinical practice? Published On: 5/17/2021...


Can Eszopiclone Augment Antidepressants?

April 26, 2021 | Podcasts

We unpack 6 studies of the hypnotic eszopiclone in depressive and anxiety disorders, and conclude that there’s more going on here than a simple benefit in sleep. Our word of the day tells us something about what’s missing in depression:...


Antidepressants in Bipolar II: What the Experts Do

April 19, 2021 | Podcasts

18 experts weigh in on how they use antidepressants in bipolar II. Sleep onset latency is defined, and we uncover the neuropsychiatric effects of marijuana in adults. Published On: 4/19/2020 Duration: 28 minutes, 11 seconds Transcript: Today, 18 experts weigh in on...


Do Benzos Treat Depression?

April 5, 2021 | Podcasts

Around 50 controlled trials have tested benzodiazepines in depression, and the results are surprising. They seem to work. In this episode we look at the controversies surrounding this research and what it means for practice. Published On: 4/5/2021 Duration: 25...


COVID, Benzos, and Opioids

March 29, 2021 | Podcasts

Overdose deaths have been rising during COVID, but simply stopping the drug causes problems of its own. In this episde, Ashwin Patkar and Richard Weisler discuss how to reduce the risk of opioid deaths in psychiatric patients. Their Current Psychiatry...