Second generation antipsychotics (SGAs) have significant side effects, which has led us at Carlat to recommend conservative use. This research update adds to concerns about increased mortality, especially at higher doses, making conservative use of SGAs a necessity.

It was once thought that moderate alcohol intake was protective against cardiovascular disease. However, new research has revealed flaws in the methodology of these old studies and instead finds that even in moderation, alcohol does not have health benefits and can increase mortality at lower doses than once thought, particularly for women.