Chris Aiken, MD, and Sarah Rivelli, MD.Dr. Aiken and Dr. Rivelli have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.
A new warning now sits beneath the list of life-threatening allergic reactions that can happen with lamotrigine. The anticonvulsant is suspected of causing cardiac arrhythmias in susceptible patients by slowing ventricular conduction and widening the QRS.
Does the limited research support that oxcarbazepine is a safer and more effective treatment for bipolar disorder than its FDA-approved cousin, carbamazepine? Here is an overview of the pros and cons from a previous article in The Carlat Psychiatry Report.Pros:Similar effectiveness as other mood stabilizers. In mania and mixed states,...
Oxcarbazepine is thought of as a kinder, gentler cousin of carbamazepine, but it brings new safety issues of its own and does not fully escape the drug interactions that hinder carbamazepine. We pull on the published and unpublished trials to figure out where this anticonvulsant stands in bipolar disorder.