This study suggests that standard doses of lithium may delay or prevent dementia in patients with bipolar disorder.

With numerous treatment options available for bipolar depression and mania, clinicians often struggle to navigate between medication classes in balancing side effects, efficacy, and costs. Dr. Beyer shares his expertise in choosing first-, second-, third-, and fourth-line options based on their evidence in older adults.

In older adults, mania is more likely to be secondary to a medication or due to a neurological or
medical illness. We provide a mnemonic to help systematically think through the most likely
causes of secondary mania, which can help guide our workup.