Many patients report that marijuana improves their pain. Their experience has a grain of truth to it, but not enough to classify cannabis as an analgesic.

Recent trials cast doubt on prazosin’s role in PTSD, but there are reasons to doubt their results.

In this QA, we discuss how to use the PICOT method to efficiently frame the clinical questions that arise in everyday practice. We also examine the hierarchy in terms of the types of studies that are most useful for the busy clinician to look at and provide a corresponding table covering the categories of evidence for clinical practice.