Bipolar depression - Articles | CARLAT PUBLISHING

Depression Rarely Travels Alone

March 7, 2026

We tend to blame the meds.

But what if the real reason a patient isn’t improving… is because we’re treating the wrong thing?

Clinical Update

New Combination Therapies

November 1, 2025

David Liebers, MD

David Liebers, MD. Research Assistant Professor of Psychiatry, NYU Langone, Department of Psychiatry.

Dr. Liebers reports he is the principal investigator for Autobahn Therapeutics. Relevant financial relationships listed for the author have been mitigated. Dr. Aiken has reviewed this educational activity and has determined that there is no commercial bias as a result of this financial relationship.

With few new psychiatric drugs on the horizon, researchers are turning to creative combinations of old standbys to tackle tough cases of addiction and beyond.

Research Update

LAIs for Bipolar Disorder

November 1, 2025

Kamron Fariba, MD

Kamron Fariba, DO. Dr. Fariba has no financial relationships with companies related to this material.

Long-acting injectables extend stability in bipolar disorder, delaying relapse more effectively than oral antipsychotics

How to Start a Psych Medication

August 4, 2025

Chris Aiken, MD and Kellie Newsome, PMHNP

Before you cook, oil the pan; before you plant that spring lawn, aerate the soil. Before you start a psych med, these are six things you need to have in place.

Research Update

Antipsychotic Dosing: Differences Between Bipolar Mania and Schizophrenia

August 1, 2024

Kate J. Travis, MD

Kate Travis, MD. Dr. Travis has no financial relationships with companies related to this material.

Conventional wisdom suggests that antipsychotics need similar doses for mania and schizophrenia. This analysis clarifies the exceptions.

Expert Q&A

Lithium, Antidepressants, and Bipolar Disorder

February 1, 2024

Michael J. Gitlin, M.D.

Michael J. Gitlin, MD.

Professor of Clinical Psychiatry and Director of the Mood Disorders Clinic at the David Geffen School of Medicine at UCLA; coauthor of The Essential Guide to Lithium Treatment (Springer, 2016).

Dr. Gitlin has no financial relationships with companies related to this material.

Practical updates on lithium, antipsychotics, and antidepressants in bipolar disorder.

Expert Q&A

Treating Bipolar Disorder During Pregnancy

October 3, 2023

Lauren Osborne, MD

Lauren Osborne, MD.

Vice Chair of Clinical Research, Department of Obstetrics & Gynecology, Weill Cornell Medicine, New York, NY.

Dr. Osborne has no financial relationships with companies related to this material.

The management of bipolar disorder during pregnancy can be tricky. Some medications can be harmful to the fetus, and others need to be adjusted carefully due to changes in kidney and liver function. We walk you through the important considerations to keep in mind when working with these patients.

Bipolar Upgrade 7: Social Rhythm Therapy

October 2, 2023

Chris Aiken, MD and Kellie Newsome, PMHNP

Social Rhythm Therapy helps patients regulate their circadian rhythm. It treats bipolar disorder, and here we show how to weave it in with medication therapy.

Research Update

Mitochondrial Modulators and Bipolar Depression

September 1, 2023

Simon M. Dosovitz, MD

Simon M. Dosovitz, MD. Dr. Dosovitz has no financial relationships with companies related to this material.

Mitochondria regulate the body’s energy stores, and they are thought to play a causal role in bipolar disorder. This analysis gathered at seven therapies that improve mitochondrial function and looked at how they work in bipolar disorder.

Clinical Update

How to Identify and Treat Prodromal Symptoms of Bipolar Disorder and Schizophrenia

September 1, 2023

José S. Sanchez-Cruz, MD

José S. Sanchez-Cruz, MD. Chief Resident, Department of Psychiatry, NYU Langone Health, New York. Chris Aiken, MD. Editor-in-Chief, The Carlat Psychiatry Report; Assistant Professor, NYU Langone Department of Psychiatry; practicing psychiatrist, Winston-Salem, NC.

Dr. Sanchez-Cruz and Dr. Aiken have no financial relationships with companies related to this material.

Patients with genetic risks for schizophrenia and bipolar disorder often present with prodromal symptoms of the illness, but the most effective treatment may surprise some. It’s not a medication.