Researchers compares treatments for antipsychotic-induced akathisia, highlighting options that may offer relief with fewer side effects.

Five strategies to reduce prolactin on antipsychotics tested in this meta-analysis

Esketamine outperforms quetiapine in TRD remission rates, but the clinical significance of this difference remains uncertain.

How long should you wait before making changes after initiating an antipsychotic? The current study tested if early efficacy on an antipsychotic predicts subsequent efficacy, and its findings indicate benefits may be observed as quickly as two weeks. 

Conventional wisdom suggests that antipsychotics need similar doses for mania and schizophrenia. This analysis clarifies the exceptions.

Patients with atypical parkinsonism are less responsive to levodopa, and psychiatric medications can exacerbate motor symptoms. Dr. Flaherty advises how to choose the right treatment in patients with parkinsonism accompanied by psychosis, apathy, anxiety, and depression.

The findings of this large study offer some reassurance about the safety and efficacy of antipsychotic polypharmacy, despite general treatment guidelines cautioning against it.

We highlight the profound difference early intervention makes in the trajectory of psychotic disorders, reducing symptom severity, suicide risk, and functional impairment.

Another trial questions the benefits of antipsychotics in delirium.