Xylazine is a non-opioid sedative commonly added surreptitiously to illicit opioids. One particularly challenging adverse effect of xylazine exposure is the development of peripheral wounds, some of which can be severe, necessitating surgical intervention and even amputation. In this interview, Dr. D’Orazio teaches us how these wounds might be caused, how to discuss them with your patients, and the best treatment approach.

Substance use is associated with many dental problems, some of which can even be life threatening. Here, Dr. Ouanounou discusses which specific dental issues addiction treatment providers need to be on the lookout for. He covers the basics of dental examination and teaches us when referral to specialty care is warranted.

Researchers compare outcomes in patients who take buprenorphine for shorter and for longer. Their findings are revealing.

Cannabis withdrawal is a largely underappreciated phenomenon that nonetheless interferes with many patients’ ability to stop using cannabis. Dr. Budney discusses some of the symptomatology of cannabis withdrawal and reviews how to discuss it with our patients.

Substance use disorders are highly comorbid with one another and it is therefore common to have patients presenting for care withdrawing from multiple substances at one time. Here, Dr. Rastegar discusses how to assess patients with multiple withdrawal syndromes and how to treat them.