Psychotherapy and medication management are the two cornerstones of addiction treatment, but they are not equally effective across different substance use disorders. This article reviews evidence from both therapeutic approaches and introduces the concept of a treatment spectrum, with medication on one end and therapy on the other. This spectrum can be a useful framework when discussing treatment options with patients and in treatment planning.

The findings of this large study offer some reassurance about the safety and efficacy of antipsychotic polypharmacy, despite general treatment guidelines cautioning against it.

This comprehensive study highlights the need for gender-specific treatment in schizophrenia spectrum disorders, revealing that hormonal changes call for lower antipsychotic doses for female patients under 45 and higher doses for those who are post-menopausal.