A history of violence in first-episode schizophrenia may guide antipsychotic selection and influence treatment outcomes.

Recent data sheds light on hallucinogen-related emergency visits.

Lurasidone was heralded as a game changer when it first gained FDA approval for bipolar depression in 2013. In 2023, this article covers what that means for patients with bipolar disorder and schizophrenia who can now afford its $10–$20/month cost.

It’s difficult to find options when clozapine does not work.

What are psychotic-like experiences (PLE) in children and teens, and what is the prognosis for those who have them? Should we treat immediately with antipsychotics? Watch and wait? Our interview with Dr. Kristin Cadenhead gives you the guidance you need to assess and manage PLE.

How long should we wait before changing an antipsychotic that doesn’t seem to be working? A large multicenter study finds that minimal symptom improvement by weeks two to four strongly predicts treatment failure and suggests an earlier switch can improve outcomes in schizophrenia.

Estrogen therapy may improve schizophrenia symptoms in women, highlighting its potential role as an adjunctive treatment.