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Home » Keywords » research_updates

Items Tagged with 'research_updates'

ARTICLES

Polypharmacy in Schizophrenia

February 10, 2020
Jason Mallo, DO
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Jason Mallo, DO. Dr. Mallo has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Polypharmacy is often practiced in schizophrenia, but you have to look hard to find any evidence that it helps. These two large-scale studies lend some empiric support to the practice, but also give us insights into how it could go wrong.
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Antidepressants Don’t Raise Dementia Risk, With One Exception

May 8, 2019
Rehan Aziz, MD.
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Rehan Aziz, MD. Dr. Aziz has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Depression is a risk factor for dementia, but can antidepressants change that risk? Some, like paroxetine (Paxil), have anticholinergic properties that can impair cognition. This study looked at what that means for the risk of dementia.
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Lisdexamfetamine for BED: How Effective Over the Long Term?

April 1, 2018
Robert T. Rubin, MD, PhD.
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Robert T. Rubin, MD, PhD. Dr. Rubin has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Lisdexamfetamine (Vyvanse) is an extended release amphetamine-based stimulant that is approved for both ADHD and binge eating disorder (BED).
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Is There a Connection Between Hormonal Contraception and Suicide?

April 1, 2018
Adam Strassberg, MD.
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Adam Strassberg, MD. Dr. Strassberg has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Clinical evidence is growing regarding an association between hormonal contraception and mood disturbances (Skovlund CW et al, JAMA Psychiatry 2016;73(11):1154–1162), and recently researchers at the University of Copenhagen published a study attempting to correlate hormonal contraceptive use with suicidal thinking and behavior.
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Does Guanfacine Affect Tic Severity in Children With Chronic Tic Disorders?

November 1, 2017
Arian Ayon Verduzco, Pharm.D candidate (2018)
From The Carlat Child Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Arian Ayon Verduzco, Pharm.D candidate (2018) Ms. Verduzco has disclosed that she has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Tic disorders, including Tourette’s, often co-occur with ADHD, OCD, and anxiety disorders. Guanfacine is often tried for all of these conditions. Randomized placebo-controlled trials of immediate release guanfacine have been mixed, with one showing 31% improvement in tics but another showing no significant improvement.
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Aripiprazole Augmentation May Improve Remission Rates in MDD

November 1, 2017
Ricardo Arechiga, PharmD candidate (2018)
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Ricardo Arechiga, PharmD candidate (2018) Mr. Arechiga has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
It seems like an endless debate: When a patient does not respond to the first trial of an antidepressant, what should we do? Switch to something else? Augment with another agent? If the latter, how often should that augmenting agent be an atypical antipsychotic?
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Fluoxetine Plus CBT for Somatic Symptom Disorder

November 1, 2017
Shirley Tsai
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Shirley Tsai PharmD candidate (2018) Ms. Tsai has disclosed that she has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Somatic symptom disorder (formerly known as hypochondriasis) is pretty common, with a prevalence of 5%–7%, and is much more likely to afflict women than men, with a gender ratio of about 10:1. While both psychotherapy and SSRI treatment are helpful, there is limited evidence about the efficacy of combining therapy with medication. A new study sought to remedy this gap.
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Does Methylphenidate Use in Children and Young Adults Increase Risk of Suicide?

November 1, 2017
Arian Ayon Verduzco. Pharm.D candidate (2018)
From The Carlat Child Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Arian Ayon Verduzco. Pharm.D candidate (2018) Ms. Verduzco has disclosed that she has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Some studies have indicated that patients with ADHD may be at an increased risk of suicide. While these studies have shown associations between methylphenidate use and suicide, it is not clear whether the stimulant actually causes suicidality or whether patients taking stimulants are suicidal for other reasons.
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Take The CME Post-Test for Dual Diagnosis, CATR, August 2017

August 1, 2017
From The Carlat Addiction Treatment Report
Issue Links: Learning Objectives | Editorial Information
The post-test for this issue is available for one year after the publication date to subscribers only. By successfully completing the test you will be awarded a certificate for 1 CME credit.
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Which Are the Most Dangerous Antidepressants?

June 1, 2017
Daniel Carlat, MD
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Daniel Carlat, MD Editor-in-chief, The Carlat Psychiatry Report Dr. Carlat has disclosed that they have no relevant financial or other interests in any commercial companies pertaining to this educational activity.
We often prescribe antidepressants to patients who are suicidal, and unfortunately, some people use these very medications to try to kill themselves. It’s been known for some time that tricyclic antidepressants are among the most toxic in overdose, so we embraced the SSRIs and later medications in part because they are considered to be safer. But how safe are they?
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