Effects of Drug Interactions
The Carlat Psychiatry Report, Volume 16, Number 11 & 12, November 2018
Neil Sandson, MD
Clinical Associate Professor, Department of Psychiatry at University of Maryland School of Medicine
Dr. Sandson has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
When it comes to computer alerts for drug interactions, the two issues to pay attention to are toxicity and loss of efficacy. Toxicity is the bigger concern, particularly if the drug has a “narrow therapeutic index,” where modest differences in the level can have dangerous effects.