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Home » psychopharmacology

Articles Tagged with ''psychopharmacology''

Tips on Choosing an Antipsychotic for Schizophrenia

August 26, 2020
Which antipsychotics should we consider selecting as the first-line and second-line treatments, and what should we base this decision on? Dr. Aziz addresses this in a past article from The Carlat Psychiatry Report. Here’s some of his advice:Process: Tolerability instead of efficacy should be considered when selecting a first-line treatment.
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CLINICAL Q&A

The Modafinils in Bipolar Depression

June 10, 2020
Chris Aiken, MD.
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Chris Aiken, MD. Editor-in-Chief of TCPR. Practicing psychiatrist, Winston-Salem, NC. Dr. Aiken has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Provigil and Nuvigil, the modafinils, may not work for full depressive episodes, but they do something else in bipolar disorder that’s important to patients. This article explores their cognitive effects, as well as their potential to cause addiction and mania.
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Trazodone: The Forgotten Antidepressant

May 7, 2020
Eugene Rubin, MD
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Eugene Rubin, MD Private practice, Bingham Farms, MI. Dr. Rubin has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Trazodone is rarely used as an antidepressant, and that’s a missed opportunity. It lacks the weight gain, sleep disruption, and sexual side effects that so many antidepressants cause. In this article are two important dosing tips that can make it work better.
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Research Theme Park: Medland

April 20, 2020
Lithium takes on the coronavirus. Benzos impair facial recognition. Antipsychotic doses find their maximum, the profile of a lithium responder, and topiramate for compulsive shopping.Published On: 4/21/20Duration: 13 minutes, 51 secondsStudies Referenced: Garcez H, Fernandes C, Barbosa F, et al. Effects of benzodiazepines administration on identification of facial expressions of...
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7 Clozapine Tips

April 8, 2020
We're supposed to move to clozapine after two failed antipsychotics in schizophrenia, but how many of us are really doing that?  Not enough. Clozapine may be difficult to use, but it is life changing for many patients. Here we bring you 7 tips, from serum plasma levels to little-known side...
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How to Dose an Antidepressant

April 3, 2020
Some antidepressants get better as the dose goes higher, while others just fizzle. For older patients, the side effects stack up as the benefits plateau. We review 3 new meta-analyses on antidepressant dosing, and bring you 4 updates on how the coronavirus is changing practice regulation.Date Published: 3/30/2020Duration: 27 minutes,...
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How to Choose an Antipsychotic in Schizophrenia

March 30, 2020
Rehan Aziz, MD.
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Rehan Aziz, MD. Associate Professor of Psychiatry and Neurology, Rutgers Robert Wood Johnson Medical School. Dr. Aziz has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Atypical antipsychotics are more alike than different, but a few stand out for tolerability, while others may have an edge for negative symptoms or for overall efficacy.
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The Psychopharmacology Algorithm Project

March 30, 2020
David Osser, MD
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
David Osser, MDDavid Osser, MD

General Editor of the Psychopharmacology Algorithm Project at the Harvard South Shore Psychiatry Residency Training Program and Associate Professor of Psychiatry at Harvard University. Dr. Osser has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Dr. Osser set out to develop a psychopharmacology algorithm that actually changes practice. He speaks to us on antidepressants in bipolar, psychoses that don’t need antipsychotics, and his top picks for bipolar mania, bipolar depression, and unipolar depression.
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Oxcarbazepine: Close, but no Cigar

March 9, 2020
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
Oxcarbazepine is thought of as a kinder, gentler cousin of carbamazepine, but it brings new safety issues of its own and does not fully escape the drug interactions that hinder carbamazepine. We pull on the published and unpublished trials to figure out where this anticonvulsant stands in bipolar disorder.
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Lumateperone and lemborexant

March 9, 2020
From The Carlat Psychiatry Report
Issue Links: Learning Objectives | Editorial Information | PDF of Issue
The antipsychotic lumateperone (Caplyta) and the hypnotic lemborexant (Dayvigo) are the newest in their class. Both of them claim to improve on the safety of older medications, and we look at the data to see how those claims hold up.
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