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How to Switch ADHD Meds Safely

October 29, 2025

Daniel Carlat, MD

Most patients don’t stay on the first stimulant we try. Here’s how to switch safely, without the confusion.

Part 1: Med Fact Book Mini-Series

Clinical Update

ADHD Update 2025: New Treatments and Current Approaches for Co-Occurring Conditions

July 1, 2025

Anne Buchanan, DO

Anne Buchanan, DO. Child and adolescent psychiatrist; Medical Director, Caring Transitions Program, NYC Health + Hospitals, New York, NY.

Dr. Buchanan has no financial relationships with companies related to this material.

Where is ADHD care today? This comprehensive update covers the latest stimulant formulations, nonstimulant innovations, and digital therapeutics. We also provide evidence-based approaches for managing ADHD with common comorbidities including anxiety, depression, autism, bipolar disorder, and psychosis.

Clinical Update

How to Select a Stimulant for Adult ADHD

March 1, 2025

Greg Malzberg, MD

Gregory Malzberg, MD. Attending Psychiatrist & Assistant Clinical Professor, Mount Sinai West, New York, NY. Creator, PsychoFarm.

Dr. Malzberg has no financial relationships with companies related to this material.

We have 30 stimulant formulations, but do all deserve prizes? We find a few with niche advantages, and three that rise to the top.

Clinical Update

Boost or Bust: Navigating the Risks of Prescription Stimulants

October 1, 2024

David Stiffler, MD and Noah Capurso, MD

David Stiffler, MD. Clinical Associate Professor of Psychiatry and Medical Director of the Steven A. Cohen Military Family Center at NYU Grossman School of Medicine, New York, NY.

Noah Capurso, MD, MHS. Associate Professor of Psychiatry, Yale University, and Editor-in-Chief, The Carlat Addiction Treatment Report.

Drs. Stiffler and Capurso have no financial relationships with companies related to this material.

Prescription stimulants, while effective for treating ADHD, are widely taken without a prescription, particularly by young adults for cognitive enhancement, weight loss, and recreational purposes. This misuse poses serious risks, from developing stimulant use disorder to experiencing severe cardiovascular and psychiatric effects. In this article, you'll learn about the prevalence and patterns of stimulant misuse, its associated dangers, and tips on how to manage it in clinical practice.

Fact Sheet

Amphetamine (Adzenys XR-ODT, Dyanavel XR, Evekeo) for Children and Adolescents

September 1, 2023

Joshua Feder, MD, Elizabeth Tien, MD, and Talia Puzantian, PharmD, BCPP

Dr. Feder, Dr. Tien, and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Newer formulations of an old drug come with a high price tag. Stick to the usual amphetamine products like mixed amphetamine salts unless liquid or ODT dosing is absolutely necessary.

Risk of Psychosis With Stimulants in ADHD Patients

June 11, 2019

Pavan Madan, MD

Pavan Madan, MD Dr. Madan has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

As of 2007, the FDA requires stimulant manufacturers to warn of possible psychosis with stimulant use. This article analyzes the results of a 2019 study comparing the risk of psychosis between methylphenidate and amphetamine classes of medications.