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Research Update

Some Antidepressants May Help Longer Than Others

April 1, 2025

Jeremy Mills, DNP, PMHNP-BC

Jeremy Mills, DNP, PMHNP-BC. Dr. Mills has no financial relationships with companies related to this material.

A large Danish study ranks antidepressants by their preventative effects.

CARLAT WEBINAR

Carlat Psychiatry News - Stimulant Fraud • Oral Ketamine • E-Cigarettes • Benzo Tapering • CBD

September 17, 2024

Chris Aiken, MD, Greg Malzberg, MD, and Kellie Newsome, PMHNP

0.25 CME Credits. In this episode, we explore nine groundbreaking stories in mental health and psychiatric medicine, covering everything from healthcare fraud to the latest advancements in drug trials. First, we dive into the recent charges brought by the US Department of Justice against executives at Done, a California-based telehealth company, for alleged healthcare fraud. Done is accused of prescribing over 40 million Adderall pills to patients without proper evaluation, raising concerns about the balance between increasing mental healthcare access and responsible prescribing practices.

Research Update

Sertraline in Schizophrenia

May 1, 2024

Richard Moldawsky, MD

Richard Moldawsky, MD. Dr. Moldawsky has no financial relationships with companies related to this material.

This study investigates whether augmenting risperidone with sertraline can improve negative symptoms.

Clinical Update

Diagnosing and Treating Postpartum Depression

October 3, 2023

Amanda Koire, MD, PhD

Amanda Koire, MD, PhD. Brigham and Women’s Hospital, Harvard Medical School, Boston, MA. Dr. Koire has no financial relationships with companies related to this material.

Postpartum depression is surprisingly common, yet often missed. We discuss screening techniques to ensure you won’t miss it, and share treatment approaches, including novel strategies like brexanolone, zuranolone, and TMS.

Research Update

Which SSRI Is Best for Panic Disorder?

August 7, 2023

Rushaniya Khairova, MD, PhD.

Rushaniya Khairova, MD, PhD. Dr. Khairova has no financial relationships with companies related to this material.

Two SSRIs emerge as top choices for panic disorder in this network meta-analysis.

Clinical Update

Treating Irritability in Autism: Functional and Medication Approaches

April 1, 2023

Joshua Feder, MD

Joshua D. Feder, MD. Editor-in-Chief, The Carlat Child Psychiatry Report.

Dr. Feder has no financial relationships with companies related to this material.

Antipsychotics can be very effective for irritability in autism, but they are often unnecessary, and the side effects are truly problematic. Don’t be the prescriber who hears irritability in autism and immediate prescribes antipsychotics. There are usually multiple steps to try before using the FDA approved antipsychotic medications.

SSRIs and Intracerebral Hemorrhage Risk

May 21, 2021

Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Dr. Barkopoulos has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

SSRIs help relieve post-stroke depression but increase the risk of intracerebral hemorrhage. This study gives us tips to reduce this risk.

Can Antidepressants Prolong Survival in Cancer Patients?

May 21, 2021

Paul Barkopoulos, MD.

Paul Barkopoulos, MD. Dr. Barkopoulos has disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.

Antidepressant adherence is linked with increased survival among cancer patients.

How to Select an SSRI

November 12, 2020

Chris Aiken, MD.

Chris Aiken, MD. Editor-in-Chief of TCPR. Practicing psychiatrist, Winston-Salem, NC. Dr. Aiken has disclosed that he has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

After digging through 3 decades of research, we can tell you this: There is no such thing as “the best” SSRI. But there are some important differences between them, and this article will show you how to find the right one for your patient.

Optimal Antidepressant Doses in Major Depression

March 9, 2020

Kristen Gardner, PharmD.

Kristen Gardner, PharmD. Dr. Gardner has disclosed that she has no relevant financial or other interests in any commercial companies pertaining to this educational activity.

More is not necessarily better in psychopharmacology. Some medications have plateau effect, while others follow a “U-shaped curve,” causing more problems as the dose goes too high. This metaanalysis looked at 77 dose-response trials with antidepressants to quantify their optimal therapeutic window.