Can a One-Week Naltrexone Detox Reduce Outpatient Opioid Relapse Rates?
The Carlat Addiction Treatment Report, Volume 5, Number 3, May 2017
Kirsten Pickard, BA
Ms. Pickard has disclosed that she has no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Naltrexone is an opioid blocker that is FDA-approved for the treatment of alcoholism. However, it is also effective off-label for treating opioid use disorder. The medication comes in two forms: an oral pill (brand name ReVia) and an injectable version (XR naltrexone, or Vivitrol). XR naltrexone is composed of 380 mg of naltrexone, given as an intramuscular injection once a month. During that month, patients who try to use opioids will feel little if any high. This works well to prevent relapse if patients keep getting the shot.