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Home » Topics » General Psychiatry

General Psychiatry
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Fact Sheet

Temazepam (Restoril) Fact Sheet [G]

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Puzantian and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Temazepam has the advantages of a short half-life and no active metabolites, and is therefore less likely to cause next day sedation. 


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Fact Sheet

Suvorexant (Belsomra) Fact Sheet

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Suvorexant is an orexin receptor antagonist, and as such it treats insomnia differently from existing agents (though lemborexant and daridorexant have since followed in its footsteps). 


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Fact Sheet

Ramelteon (Rozerem) Fact Sheet [G]

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Puzantian and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Ramelteon is a melatonin receptor agonist.


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Fact Sheet

Doxepin (Silenor) Fact Sheet [G]

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Puzantian and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Low-dose doxepin is effective for sleep maintenance insomnia and is generally well tolerated at hypnotic doses, with minimal anticholinergic effects compared to higher antidepressant doses.


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Fact Sheet

Buspirone (BuSpar) Fact Sheet [G]

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Puzantian and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Buspirone is a non-benzodiazepine anxiolytic that is not habit-forming and does not cause sedation, but it takes time to work and is less effective for acute anxiety.


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Fact Sheet

Antihistamines (Diphenhydramine, others) Fact Sheet [G]

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Puzantian and Dr. Carlat have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Antihistamines can be very effective sleep aids for many patients, although some patients may experience too much grogginess (“hangover”) in the morning.


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Fact Sheet

Ziprasidone (Geodon) Fact Sheet [G] for General Psychiatry

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Carlat and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Ziprasidone has an appealing weight and metabolic profile, but many clinicians are overly cautious due to its reputation for QT interval prolongation.


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Fact Sheet

Trifluoperazine (Stelazine) Fact Sheet [G] for General Psychiatry

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Carlat and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Trifluoperazine, like thiothixene (Navane), is an effective older agent with similar potency to haloperidol or fluphenazine; however, given the wide range of antipsychotic options today, it is rarely used.


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Fact Sheet

Thiothixene (Navane) Fact Sheet [G] for General Psychiatry

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Carlat and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Thiothixene is one of the original high-potency first-generation antipsychotics (FGAs)—but most clinicians prefer fluphenazine or haloperidol due to greater familiarity and more formulation options (liquid, injectable, long-acting).


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Fact Sheet

Thioridazine (Mellaril) Fact Sheet [G] for General Psychiatry

January 1, 2026
Daniel Carlat, MD and Talia Puzantian, PharmD, BCPP

Dr. Carlat and Dr. Puzantian have no financial relationships with companies related to this material.
Full Fact Sheet Editorial Information

Thioridazine prolongs the cardiac QT interval more than any other antipsychotic, rendering it too risky for the majority of patients.


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